This scientist is helping build a missing map of childhood 这位科学家正在帮助构建儿童发育的缺失图谱

Deanne Taylor, director of bioinformatics at CHOP, championed the inclusion of pediatric data in the Human Cell Atlas after discovering the original project only planned to study adults The NIH awarded a $38.5 million grant in 2021 to the Developmental Genotype-Tissue Expression Project (dGTEx) to create the first comprehensive database of healthy pediatric tissue gene expression Children's cells differ from adults' in gene expression patterns, leading to drastically different and sometimes dead Deanne Taylor发现人类细胞图谱(Human Cell Atlas)仅聚焦成人，缺乏儿童数据，推动建立dGTEx项目填补空白 NIH于2021年资助3850万美元建立dGTEx项目，创建首个全面健康儿童组织基因表达数据库 儿童基因表达与成人存在显著差异，影响药物反应和疾病治疗，忽视儿童数据会错过关键干预窗口 dGTEx数据将整合至人类细胞图谱的儿童板块，推动精准儿科医学和发育生物学研究 Taylor同时主导Kids First数据资源中心和HubMAP等协作项目，促进跨机构生物医学数据标准化